منابع مشابه
Hematologic disorders associated with primary mediastinal nonseminomatous germ cell tumors.
BACKGROUND The association between primary germ cell tumors of the mediastinum (the space between the lung pleura that contains the heart and other chest viscera) and hematologic malignancies has been described by retrospective analysis of patients treated at individual clinical centers. To better characterize the risk of hematologic disorders in patients with extragonadal germ cell tumors and ...
متن کاملExuberant Vasculoconnective Component in Mediastinal Mixed Germ Cell Tumors
We aimed to evaluate the histologic components of primary mediastinal mixed germ cell tumors. A total of 221 patients diagnosed with a mediastinal germ cell tumor (GCT) were retrospectively reviewed. Among them, 14 patients underwent surgical resection after chemotherapy and 8 patients were diagnosed with mixed GCT, who were then selected for further evaluation. Clinical chart review and histol...
متن کاملA Study of Patients with Primary Mediastinal Germ Cell Tumors Treated Using Multimodal Therapy
OBJECTIVES Primary mediastinal germ cell tumors (PMGCTs) are rare, which often makes them difficult to treat. Herein, we examined patients with PMGCTs who underwent multimodal treatment. METHODS We examined 6 patients (median age: 25 years, range: 19-27 years) with PMGCTs who underwent multimodal treatment between April 2001 and March 2015. Three patients had seminomas, 2 patients had yolk sa...
متن کاملManagement of the primary malignant mediastinal germ cell tumors: experience with 54 patients
BACKGROUND Primary malignant mediastinal germ cell tumor (PMMGCT) is rare and sometimes the prognosis of the patients with PMMGCT is not very satisfactory. METHODS A total of 54 patients with PMMGCT in a follow-up from 1990 to 2009. We evaluated the role of the surgical treatment and the effect of multimodality treatment strategy for patients with PMMGCT. RESULTS Fifty-two patients underwen...
متن کاملSecondary malignant melanoma in primary mediastinal germ cell tumour.
Secondary transformation in Germ Cell Tumours (GCT) is an extremely rare event. We report here a case of malignant melanoma arising in primary mediastinal GCT. A young male presented with new onset dyspnoea and a mediastinal mass. As serum alpha fetoprotein was raised, a diagnosis of primary mediastinal GCT was made. He achieved remission with standard chemotherapy and resection of the mass. Af...
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ژورنال
عنوان ژورنال: Cancer
سال: 1974
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197403)33:3<763::aid-cncr2820330323>3.0.co;2-e